HPMC VS Methyl Cellulose: What’s The Difference?

In vertical applications such as tile adhesives and exterior coatings, HPMC provides sag resistance, preventing the material from sliding or slumping during application.

Data on chronic toxicity and carcinogenicity are available for microcrystalline cellulose (E 460), methyl cellulose (E 461) hydroxypropyl cellulose (E 463), HPMC (E 464) and sodium carboxymethyl cellulose (E 466). Some studies were unfit for evaluation due to methodological shortcomings. In the only relevant study, the dietary administration of even high doses of microcrystalline cellulose (E 460) (30%, 15,000 mg/kg bw) to rats for 72 weeks did not affect survival, feed efficiency or haematology. Apart from some dystrophic calcification in renal tubules, no other relevant lesions were noted and tumour incidence did not differ with that of controls. Several studies were conducted in rats with methyl cellulose (E 461) via feed or drinking water or by gavage at concentrations up to 5% (2,500 mg methyl cellulose/kg bw per day) and for up to 2 years. For all examined parameters, no adverse effects were reported and also the observed tumours did not differ in type and number in treated and control groups. In the only identified study, the daily dosing of male and female rats (0, 1,500, 3,000 or 6,000 mg hydroxypropyl cellulose/kg bw) via gavage for 6 months did not cause adverse effects (including carcinogenicity) apart from a decrease in body weight in high-dosed rats (statistically significant in females only). Apart from a decrease in body weights of high-dosed males, no other significant adverse findings were reported and there was no indication of a carcinogenic effect in rats of either sex dietary exposed to HPMC (E 464) up to 20% (10,000 mg/kg bw per day) for 1 year. Carboxy methylcellulose (E 466) was tested in mice and rats at dosages of 0, 10,000 or 100,000 mg/kg diet (equivalent to 0, 1,500 or 15,000 mg/kg bw per day for mice and to 0, 500 or 5,000 mg/kg bw per day for rats) for up to 104 weeks. Despite the increase in feed intake, a treatment related decrease in body weight was noted at the end of the treatment. Histological examination revealed no intestinal abnormality or evidence of the passage of the additive across the intestinal wall in either species and the tumour incidences were comparable among groups.

High viscosity (150,000-200,000) is mainly used for polystyrene particle insulation mortar powder and vitrified microbead insulation mortar. The higher viscosity helps prevent mortar from dusting and sagging, improving the construction process.

Low-viscosity hydroxypropyl methylcellulose is mainly used for self-leveling mortar. Its viscosity is low, although its water retention is poor. HPMC 's leveling property is good, and the mortar is dense. Medium and low-viscosity HPMC is mainly used in tile adhesives, joint fillers, anti-cracking mortars, and thermal insulation mortars. It has good constructability, a good water retention effect, and high mortar density. HPMC exists as a water-retaining agent in mortar. Its water-retaining properties prevent the paste from drying too quickly. And cracking after reapplying.

Modified Types：

According to Article 7(1) of Regulation (EC) No 1831/2003, the Commission forwarded the application to the European Food Safety Authority (EFSA) as an application under Article 10(2) (re-evaluation of an authorised feed additive). EFSA received directly from the applicant the technical dossier in support of this application. The particulars and documents in support of the application were considered valid by EFSA as of 26 April 2019.

Was ist HPMC?

4. The water-retaining property of Hydroxypropyl Methylcellulose depends on its addition amount and viscosity. With the same addition amount, the water-retention rate of Hydroxypropyl Methylcellulose Hpmc is higher than that of MC.